University of New South Wales researchers have made a discovery that could lead to a revolutionary drug that actually reverses ageing.
Our cells have a capability to repair DNA damage, but this ability declines as we age.
The scientists identified that the metabolite NAD+, which is present in every body cell, has a key role in a process that controls DNA repair.
Treating mice with a NAD+ precursor, called NMN, improved their cells’ ability to repair DNA damage caused by old age.
The cells of the old mice were indistinguishable from the young mice, after just one week of treatment.
Human trials of NMN therapy will begin within six months.